Guides
Educational guides for effects, risks, evidence, legal context and safety awareness.
Educational context only
Guides connect existing SubsAtlas profiles, comparisons and safety topics. Not use guides. Not medical advice. Not legal advice.
Featured guides
Starting points for effects, risks and evidence context.
THC vs CBD: effects, risks and evidence
THC is the primary intoxicating compound in cannabis. CBD does not produce intoxication. Their risk profiles, evidence bases and legal contexts differ substantially.
What not to mix with alcohol: interaction awareness
Alcohol is a CNS depressant with well-documented interaction risks across many substance categories. Combinations with opioids, benzodiazepines and GHB are among the most serious documented concerns.
Evidence levels explained: strong, moderate, limited and anecdotal
Evidence level describes the quality, consistency and source type of available information. It is not a safety endorsement and does not indicate that a substance is suitable for use.
Compare guides
Side-by-side educational context on related profiles. Not a recommendation or ranking.
THC vs CBD: effects, risks and evidence
THC is the primary intoxicating compound in cannabis. CBD does not produce intoxication. Their risk profiles, evidence bases and legal contexts differ substantially.
Amanita Muscaria vs Psilocybin Mushrooms: why they should not be confused
Amanita muscaria is not psilocybin. Its active compounds are muscimol and ibotenic acid — not psilocybin or psilocin. The pharmacology, effects and risks are fundamentally different.
Safety guides
Educational context on interaction concerns, risk awareness and safety topics.
Trust explainers
How SubsAtlas uses evidence levels, risk levels, source review and legal context.
Evidence levels explained: strong, moderate, limited and anecdotal
Evidence level describes the quality, consistency and source type of available information. It is not a safety endorsement and does not indicate that a substance is suitable for use.
Legal context explained: why status varies by region
Legal status is not universal. The same substance can be legal in one country, controlled in another and prohibited in a third. Status also changes over time. SubsAtlas shows legal context as educational background.
Cannabis & compounds
Educational context on cannabinoids, terpenes and related evidence uncertainty.
Kava vs Kratom: reported profiles and risk context
Kava (Piper methysticum) and kratom (Mitragyna speciosa) are different plants with different active compounds and different risk profiles. Kratom's opioid receptor activity is a fundamental distinction from kava.
Cannabis terpenes explained: aroma, evidence and uncertainty
Terpenes are aroma compounds found in cannabis and many other plants. Their role in human pharmacological effects at typical exposure levels is a subject of ongoing research with limited evidence to date.
Educational context only. Not medical advice, legal advice, dosing guidance, sourcing guidance or a use guide. Effects, risks and legal status vary by individual, product and jurisdiction.