Passionflower
Passiflora incarnata · Maypop
Traditional calming botanical with limited clinical evidence and sedative interaction concerns.
Key caution
Sedation interactions with alcohol, benzodiazepines and sleep medications
Editorial review status — shown for transparency
AI Context
Deterministic summaries of curated archive data. Not medical advice. Not a use guide.
Passionflower: profile overview
Passionflower is a botanical with limited evidence quality and a low risk profile. Traditional calming botanical with limited clinical evidence and sedative interaction concerns. Individual responses vary significantly. This summary is drawn from the curated SubsAtlas archive.
- Risk profile: Low — generally lower concern based on available evidence and known interaction context.
- Evidence quality: Limited — early or narrow research — uncertainty is significant.
- Key caution: Sedation interactions with alcohol, benzodiazepines and sleep medications
- Interaction concerns noted with: Alcohol, Sedatives, Benzodiazepines.
- Primary compounds: Flavonoids (including chrysin), Maltol, Harman alkaloids (trace).
Sedation interactions with alcohol, benzodiazepines and sleep medications
Limitations
- Based on curated SubsAtlas archive data only.
- Not medical advice. Not legal advice. Not a use guide.
- Individual responses vary. Source review is ongoing.
- Do not rely on this for personal decisions.
AI Context summarizes curated SubsAtlas archive data only. Not medical advice. Not legal advice. Not a use guide. No external AI calls are made.
Quick Facts
Concise educational context for orientation. Effects and risks vary.
Category
botanical
Main compounds
Flavonoids (including chrysin), Maltol, Harman alkaloids (trace)
Reported profile
Relaxation, Calming reports, Mild sleepiness
Onset range
Varies by product and person
Duration range
General educational context only
Main caution
Sedation interactions with alcohol, benzodiazepines and sleep medications
Body & Mind Map
Visual summary of reported effect patterns. Effects vary.
Community Signal
Community Signal is based on anonymous structured reports. It does not represent a recommendation.
Common warning
Community Signal requires moderated structured reports.
Risk awareness
Clear cautions, uncertainty and interaction concerns. This is not medical advice.
Main risks
- Sedation interactions with alcohol, benzodiazepines and sleep medications
- Not recommended during pregnancy
- Clinical evidence is limited and inconsistent
- Contains trace harman alkaloids — MAOI interaction potential is a theoretical concern
Avoid if…
- You have relevant medical concerns without professional guidance
- You are in an unsafe setting
- You need to drive or operate machinery
Do not combine with…
- Alcohol
- Sedatives
- Benzodiazepines
- MAOIs (theoretical concern)
Medical caution
- Review medication interactions with a qualified professional
- Seek professional help for medical concerns
Unknowns
- Product quality may vary
- Individual response varies
- Evidence may be incomplete
Interaction Warnings
Interaction concerns are shown for risk awareness only. SubsAtlas does not describe any combination as safe.
- Additive sedation concerns with CNS depressants. Trace alkaloid content raises theoretical MAOI interaction consideration. Consult a professional if taking medications.
General onset
Varies by product and person
Peak
Varies by substance, product and person
Duration
General educational context only
After effects
May vary; monitor uncertainty and risk context
Timeline ranges are general educational context, not instructions.
Sources
Evidence quality, source type and review context are separated from community patterns.
Sources need editorial review
Sources listed here have not yet completed editorial review. They are shown for transparency, not as verified citations. What source review means
Curated passionflower botanical education profile
editorial source · Reviewed 2026-05-16
Source status: needs-review · How source review works
Legal context
Legal status varies by country, state and local regulation. This is educational context only — not legal advice.
Available as a herbal supplement in most jurisdictions. Regulatory status varies.
Legal status varies by country, state and local regulation. SubsAtlas provides educational context only and does not provide legal advice, sourcing or buying guidance.
Legal context requires ongoing review as laws change. How legal context works
Similar Entries
Related educational profiles for comparison and context.
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Traditional botanical associated with calming and sleep-related reports, with mixed evidence and sedative interaction concerns.
Main caution
Additive sedation possible with alcohol, sedatives and anxiolytics
Legal: Legal context varies
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Allergy risk — particularly for individuals sensitive to ragweed or Asteraceae family plants
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Mulungu
Traditional South American botanical associated with calming and sedation reports, with limited clinical evidence and sedative interaction concerns.
Main caution
Clinical evidence is very limited
Legal: Legal context varies
Lavender
Widely used aromatic botanical associated with calming reports, with modest evidence primarily from aroma contexts and relevant allergy and sedation considerations.
Main caution
Skin sensitisation and allergy possible with concentrated essential oil
Legal: Legal context varies
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Educational information only. Not medical advice. No personalized dosing, sourcing, preparation or optimization guidance.