Valerian · Passionflower · Chamomile
Reported calming botanicals
Educational overview of three botanicals associated with calming reports: valerian, passionflower and chamomile. Covers evidence quality, risk context and sedation interaction concerns.
Interaction concern
Low concernGeneral educational visualization, not a medical prediction.
Main cautions
Additive sedation is possible when combined or taken with other sedatives
Clinical evidence for most effects is limited — treat cautiously
Educational context only. Not a use guide.
Risk signal is a general educational visualization based on profile risk levels and known interaction concerns. It is not a medical prediction.
How risk signal works →Legal status varies by country, state and local regulation. Cards are educational context only. How legal context works
Explore related profiles
Full educational profiles for the substances in this card.

Valerian
Traditional botanical associated with calming and sleep-related reports, with mixed evidence and sedative interaction concerns.
Main caution
Additive sedation possible with alcohol, sedatives and anxiolytics
Legal: Legal context varies
Passionflower
Traditional calming botanical with limited clinical evidence and sedative interaction concerns.
Main caution
Sedation interactions with alcohol, benzodiazepines and sleep medications
Legal: Legal context varies

Chamomile
Widely used traditional botanical associated with calming reports, with modest evidence and relevant allergy and sedation interaction considerations.
Main caution
Allergy risk — particularly for individuals sensitive to ragweed or Asteraceae family plants
Legal: Legal context varies
Educational information only. Not medical advice. Risk signal is a general educational visualization — not a medical prediction. Cards are not use guides or recommendations.